Trends in Pharmaceutical Biotechnology

Trends in Pharmaceutical Biotechnology (TPB) is a medium for global academics to exchange and disseminate their knowledge and the latest discoveries and advances. Trends in Pharmaceutical Biotechnology (TPB) follows a libre open access policy under the Creative Commons Attribution 4.0 International public license. The journal publishes two issues annually and All manuscripts undergo rigorous double-blind peer review to ensure scientific quality and acceptance.

Vol. 3 No. 1 (2025)

Number of pages 1-93, List of authors by countries (Egypt, Iraq, Iran, Australia and UK)

Published: June 30, 2025

Biosynthesis of Silver Nanoparticles by Bacillus subtilis and Their Anti-Leishmanial Activity in Vivo

10.57238/tpb.2025.153196.1023

Rana Saleh Al-Difaie ⁽¹⁾, Ghaidaa Abass Jasim Al-Jubouri ⁽²⁾, Rasha Saleh Sahib ⁽³⁾

(1) Department of Agricultural Biotechnology, College of Biotechnology, University of Al-Qadisiyah, Diwaniyah, Iraq ,

(2) Department of Microbiology and Parasitology, College of Veterinary Medicine, University of Al-Qadisiyah, Diwaniyah, Iraq ,

(3) Department of Chemistry, College of Science, University of Al-Qadisiyah, Diwaniyah, Iraq

1-9

Read Statistic: 139

History of Crimean–Congo Hemorrhagic Fever in Iraq: A Review

10.57238/tpb.2025.153196.1024

Ashwaq M. S. Al-Jbouri ⁽¹⁾, Nada Khazal K. Hindi ⁽²⁾, Raoof J. A. Maaroof ⁽³⁾, Ahmed Saleem Abbas ⁽⁴⁾

(1) Department of Biomedical Engineering, College of Engineering, University of Babylon, Hillah 51001, Iraq ,

(2) Department of Biomedical Engineering, College of Engineering, University of Babylon, Hillah 51001, Iraq; College of Pharmacy, Al-Mustaqbal University, Hillah, 51001, Iraq ,

(3) Department of Basic and Medical Science, College of Nursing, Babylon University, Hillah, 51001 Iraq ; College of information Technology, University of Babylon, Hillah, 51001 Iraq ,

(4) College of Science, University of Hilla; Babylon, Hillah 51001, Iraq

10-15

Read Statistic: 116

Design and Preclinical Evaluation of a Multi-Epitope mRNA Vaccine Against Methicillin-Resistant Staphylococcus Aureus (MRSA)

10.57238/tpb.2025.153196.1025

Noor Z. Kbah ⁽¹⁾, Fatemah Hasan Shkir ⁽²⁾, Saja Hussein Hashim ⁽³⁾, Qassim A. Zigam ⁽⁴⁾, Ahmed R. Ali ⁽⁵⁾

(1) Department of Pharmaceutics, College of Pharmacy, Al-Zahraa University for Women, 56001, Karbala, Iraq ,

(2) Department of Pharmaceutics, College of Pharmacy, Al-Zahraa University for Women, 56001, Karbala, Iraq ,

(3) Department of Pharmaceutical Chemistry, College of Pharmacy, University of Babylon, Hillah 51001, Iraq ,

(4) Department of Pharmacology, College of Pharmacy, Al Mustaqbal University, Hillah 51001, Iraq ,

(5) Department of Medicinal Chemistry, College of Pharmacy, Mansoura University, Mansoura, 35516, Egypt

16-35

Read Statistic: 245

CRISPR-Cas9 in Functional Genomics: Implications for Target Validation in Precision Oncology

10.57238/tpb.2025.153196.1026

Iman Fadhel Abdul-Hussin ⁽¹⁾, Mays Hassan Obais Alkhalidi ⁽²⁾, Sharafaldin Al-Musawi ⁽³⁾, Lubna Abd Muttalib Alshalah ⁽⁴⁾, Mohsen Sheykhhasan ⁽⁵⁾

(1) Department of Applied Biotechnology, College of Biotechnology, Al-Qasim Green University, Hillah, Iraq ,

(2) Department of Applied Biotechnology, College of Biotechnology, Al-Qasim Green University, Hillah, Iraq ,

(3) Department of Food Science and Technology, College of Food Sciences, Al-Qasim Green University, Hillah, Iraq ,

(4) Environmental Research and Study Center, Babylon University, Hillah, Iraq ,

(5) Cellular and Molecular Research Center, Qom University of Medical Sciences, Qom, Iran

36-48

Read Statistic: 155

Generation and Characterization of a Novel Anti-IL-17A Monoclonal Antibody for the Treatment of Psoriatic Arthritis

10.57238/tpb.2025.153196.1027

Widad Abd Aljabbar Mozzan ⁽¹⁾, Nada Khazal K. Hindi ⁽²⁾, Ashwaq M. S. Al-Jbouri ⁽³⁾, Yasmeen Ali Hussein ⁽⁴⁾, Hayder Al-Aubaidy ⁽⁵⁾

(1) Department of Pharmacology, College of Pharmacy, ‎Al-Mustaqbal University, Hillah, Iraq ,

(2) Department of Basic and Medical Science, College of Nursing, Babylon University, Hillah, Iraq ,

(3) Department of Biomedical Engineering, College of Engineering, University of Babylon, Hillah, Iraq ,

(4) Department of Pharmacology, College of Pharmacy, ‎University of Alkafeel, Najaf, Iraq ,

(5) Department of Biochemistry, New Medical Education Australia, Brisbane QLD, Australia

49-63

Read Statistic: 134

Nanocarriers in Targeted Drug Delivery: Design Strategies to Overcome Biological Barriers

10.57238/tpb.2025.153196.1028

Tiba Al Temimi ⁽¹⁾, Huda Mohammed Reda ⁽²⁾, Reda Elfeshawy ⁽³⁾, Amal Talib Al Sa'ady ⁽⁴⁾, Shatha Khazal K. Hindi ⁽⁵⁾

(1) Pharmacy College, Al-Mustaqbal University, Hillah, Iraq ,

(2) Pharmacy College, Al-Mustaqbal University, Hillah, Iraq ,

(3) Faculty of Nursing, Menofia University, Menofia, Egypt; Nursing College., Al-Mustaqbal University, Hillah, Iraq ,

(4) College of Pharmacy, University of Babylon, Hillah, Iraq ,

(5) Immunodeficiency Center in Al-Mu'allimin in the Rusafa Health Department, Baghdad, Iraq

64-69

Read Statistic: 91

An Overview: Engineering pH-Sensitive Polymeric Nanoparticles for Enhanced Intracellular Delivery of Anticancer Drugs in Hypoxic Tumors

10.57238/tpb.2025.153196.1029

Raoof Jabbar Abbas Maaroof ⁽¹⁾, Hiba Jasim Hamza ⁽²⁾, Nada Khazal K. Hindi ⁽³⁾, Mohamed AbdElrahman ⁽⁴⁾

(1) Department of Basic and Medical Science, College of Nursing, University of Babylon, Hillah, Iraq ,

(2) Department of Basic and Medical Science, College of Nursing, University of Babylon, Hillah, Iraq ,

(3) Department of Basic and Medical Science, College of Nursing, University of Babylon, Hillah, Iraq; Pharmacy College, ‎Al-Mustaqbal University, Hillah, Iraq ,

(4) Department of Clinical Pharmacy, Badr University, Cairo, Egypt; Faculty of Medicine, Helwan University, Cairo, Egypt; Faculty of Medicine, Al-Mustaqbal University, Hillah, Iraq

70-78

Read Statistic: 90

Pharmacogenomics in Personalized Oncology: From Biomarker Discovery to Clinical Implementation

10.57238/tpb.2025.153196.1030

Ghadah Ali Al-Oudah ⁽¹⁾, Sahar Kadhim Abbas ⁽²⁾, Rasha Hadi Saleh ⁽³⁾, Noor Thamer Mahmood ⁽⁴⁾, Wallaa Luay Alfalluji ⁽⁵⁾, Widad Hamza ⁽⁶⁾, Ahmed M. N. Al-Ajrash ⁽⁷⁾

(1) Pharmacy College, Al-Mustaqbal University, Hillah, Iraq ,

(2) Department of Basic and Medical Science, College of Nursing, Babylon University, Hillah, Iraq ,

(3) Department of Clinical Laboratory Sciences, College of Pharmacy, University of Babylon, Hillah, Iraq ,

(4) Department of Cyber Security, Babylon University, Hillah, Iraq; Department of Cyber Security, Al-Mustaqbal University, Hillah, Iraq ,

(5) Hammurabi Medical College, Babylon University, Hillah, Iraq; College of Medicine, Al- Mustaqbal University, Hillah, Iraq ,

(6) Department of Pediatrician, College of Medicine, Al-Mustaqbal University, Hillah, Iraq ,

(7) MBChB, MRCP (Respiratory), Respiratory Department, Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK

79-93

Read Statistic: 168

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